In the peripheral blood, CCL3 was found in 8 of 14 patients with aseptic loosening (51.5 to 92.8 pg/mL) and in 5 of 34 patients with an infection (47.5 to 118.8 pg/mL); CXCL2 was not detected in sera of patients with aseptic loosening and in 5 of 34 patients with an infection (ranging from 9.4 to 514.5 pg/mL). This evidence concerns the gene CCL3 and infection.