Our previous studies have shown that CIL and cell–cell repulsion in prostate cancer cells depend on EphA2 and EphA4 since knockdown of these receptors led to a loss of repulsion and failure of CIL (Astin et al., 2010; Batson et al., 2013; see also Fig. 6B). This evidence concerns the gene EPHA2 and prostate carcinoma.