The expression of CSPG4 in muscle cells together with the fact that it is upregulated in Duchenne muscular dystrophy, and downregulated in merosin-deficient congenital muscular dystrophy (MDC1A) muscles, respectively (Petrini et al., 2003), suggest that Perd function in myofibrillogenesis might be conserved. Here, LAMA2 is linked to congenital muscular dystrophy due to LMNA mutation.