In the three studies from the United States, the serological status of H. pylori had no impact on HOMA-IR as noted in the Sacramento Area Latino Study on Aging [10], and no impact on fasting insulin concentration (a segregate of insulin resistance) in the Third National Health and Nutrition Examination Survey [11], while it was not examined in the Multiethnic Study of Atherosclerosis [9]. The gene discussed is INS; the disease is Insulin resistance.