The A20 mutations identified in lymphoma, which are distributed throughout the gene, affect the ovarian tumour (OTU), ZnF and linker regions in DLBCL, mantle cell lymphoma (MCL), mucosa-associated lymphoid tissue (MALT), classic Hodgkin’s lymphoma (cHL), marginal zone lymphoma (MZL) and primary mediastinal B cell lymphoma (PMBL) [5]. The gene discussed is TNFAIP3; the disease is mantle cell lymphoma.