TNF and Sepsis: In addition, when we determined the plasma cytokine levels of these four proteins, we found that at one day after sepsis, the mice undergoing the CS model had significantly increased production of IL-6, IL-10, MIP1α, and TNFα in the plasma compared to mice who underwent the CLP model of sepsis (all p<0.01) (Figure 6A), correlating to their genomic expression.