These include the Bora-activating subunit of the aurora A kinase [31,32], the Wee1 kinase regulator of mitotic entry [23], the mitotic regulator Emi1 (early mitotic inhibitor 1) [44,45], the DNA replication checkpoint regulator claspin 1 [46,47], the Fanconi's anaemia group ATP-dependent RNA helicase FANCM (Fanconi's anaemia complementation group M) [48] and HSF1 (heat-shock transcription factor 1) [49]. This evidence concerns the gene FANCM and Fanconi anemia.