Using the online analytic software developed by Memorial Sloan Kettering Cancer Center (http://www.cbioportal.org/public-portal/), we have externally validated our top 3 hits in the TCGA database, in which the expressions of NETO2, GBP2, and VCAN studied by RNA-seq were consistently upregulated, respectively, in ccRCC patients. The gene discussed is GBP2; the disease is nonpapillary renal cell carcinoma.