While all the genes, except NDST2, were expressed in relatively balanced ratio in normal and BPH specimens, disbalance of the transcriptional patterns in favor to HS chains elongation stage (EXT1/EXT2) was observed in prostate tumors, where total expression level of EXT1 and EXT2 expression constituted near a half of the total enzymes expression. The gene discussed is EXT1; the disease is benign prostatic hyperplasia.