The abundant expressions of NRG1 and ErbB and the interactions of these molecules with GABAergic (Yau et al., 2003; Vullhorst et al., 2009; Neddens and Buonanno, 2010), glutamatergic (Hahn et al., 2006; Li et al., 2007), and dopaminergic neurons (Abe et al., 2009; Kato et al., 2011) imply that these molecules have critical roles in the regulation of synaptic plasticity at excitatory and inhibitory synapses that might be involved in the pathogenesis of the cognitive deficits in schizophrenia. Here, EGFR is linked to schizophrenia.