Two contiguous target regions were included: a 0.2 Mb interval, the span of the TIPARP gene and flanking regions (Chr 3: 156299721–156500330), and a 1.5 Mb region covering a portion of chromosome region 18q21.1 (Chr 18: 47749745–49250310) that is frequently subject to deletion in colon cancer (19). The gene discussed is TIPARP; the disease is colonic neoplasm.