Whereas liver weight, expressed as a percentage of body weight, was slightly lower in Ldlr-BMTCmklr1-/- mice compared to Ldlr-BMTWT mice (Ldlr-BMTWT, 5.49%±0.086; Ldlr-BMTCmklr1-/-, 5.08%±0.10, p<0.05), the Ldlr-BMTCmklr1-/- mice showed a small increase in their hepatic triglyceride content and hepatic steatosis (Fig. 4D and Fig. S3G). The gene discussed is LDLR; the disease is fatty liver disease.