In a review published in a recent issue of PLoS ONE, Liu and colleagues[12] synthesized available prospective epidemiological data on the association between ALT and incident MetS and reported a multivariate adjusted relative risk (RR) (95% confidence interval) of 1.81 (1.49–2.14) for MetS in a comparison of top versus bottom category of baseline ALT level. Here, GPT is linked to metabolic syndrome.