Interestingly, unlike the 231 genes differentially regulated between type II:MAF1 and type II infection, only eight genes were observed to be significantly induced in a MAF1-dependent manner during type I infection, including SerpinB2 and IL-11 (Figure S8); the increased expression of SerpinB2 and IL-11 receptor alpha (IL-11rap) was also MAF1-dependent during type II:MAF1 infection (Figure 6C) and might represent part of a HMA-induced signaling pathway in host cells. Here, IL11 is linked to infection.