Vaspin (a visceral adipose tissue-derived serine protease inhibitor) is a novel adipocytokine that was reported to be specifically expressed in white adipose tissue (WAT) of Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an experimental model for T2D and was postulated to have insulin sensitizing effects in state of obesity (2). Here, INS is linked to type 2 diabetes mellitus.