However, recent studies have revealed decreased expression of CXCR3 on CD4+ T cells in fulminant T1D onset, while increased CXCR3 expression levels were accompanied by mild T1D onset [29, 30], which is partly concordant with our findings, but awaits confirmation in the future studies of very close monitoring of the CXCR3 T cell changes at onset of T1D. Here, CXCR3 is linked to type 1 diabetes mellitus.