Analyses of the percentages of T memory (CD4+CD45RO+) cells in hr and lr nondiabetic FDRs, patients with sa R-T1D, and healthy controls revealed no differences (CD4+CD45RO+: 28.18 ± 5.63 versus 25.03 ± 6.26 versus 27.23 ± 8.54 versus 27.67 ± 6.59%, resp., P = NS). Here, CD4 is linked to type 1 diabetes mellitus.