TNF and rheumatoid arthritis: Since miR-125b is an evolutionary conserved miRNA that regulates signal pathways of inflammation [22], B cell differentiation [23, 24], TNF production, and apoptosis [25] that are biological pathways of importance for both lymphoma and RA, we assessed whether miR-125b is deregulated in RA and useful as potential biomarker predictive for rituximab response.