PLAT and Hyperglycemia: In an analysis of 268 patients with a non-lacunar stroke, admission hyperglycemia was negatively correlated with the degree of neurological improvement at 24 h in reperfused but not non-reperfused recombinant tissue plasminogen activator (rt-PA)-treated patients [25], suggesting the deleterious effect of hyperglycemia on infarct growth may be related to whether or not reperfusion occurs.