A genome-wide association study showed that there is a group of genes strongly associated with CAD, such as solute carrier family 22 member 3 (SLC22A3), lipoprotein(a)-like 2 (LPAL2), and lipoprotein(a) (LPA), but investigators did not identify the functional variants at these loci [10-12]. The gene discussed is LPA; the disease is coronary artery disorder.