Multiple miR-125b targets were found to be upregulated in hepatocellular carcinoma, including BCL2, BCL2 like 2 (Bcl-W), myeloid cell leukemia sequence 1 (Mcl-1), interleukin-6 receptor (IL6R), lin-28 homolog B (LIN28B) and placenta growth factor (PIGF). The gene discussed is LIN28B; the disease is hepatocellular carcinoma.