Considering that PC-derived second messengers are involved in the activation of cellular signaling mediators like mTOR and MAPKs [9, 29, 30], activation of the Akt-mTOR and MEK1/2-ERK1/2 signaling pathways by phosphatidylcholine was analyzed in the MCF-7 breast cancer cell line. Here, MAPK3 is linked to breast carcinoma.