CRP and Sepsis: While Sugitharini's study did not report sensitivity of CRP in detecting sepsis, a study comparing CRP levels in 80 septic pediatric patients in India with 30 healthy pediatric controls found that CRP had a sensitivity of 67%, specificity 97%, PPV 98%, and NPV 53%; this study found a higher sensitivity and specificity for TNF-alpha levels (sensitivity 85%, specificity 100%, PPV 100%, and NPV 71%) [46].