Combination models have also been evaluated in neonatal sepsis evaluating four tests (microerythocyte sedimentation rate, immature to total neutrophil count, morphological changes in neutrophils, and CRP) and found the role of these tests in early diagnosis of neonatal sepsis were statistically significant (P < 0.05) with a combination of three or all of these four tests was highly specific (95–100%) [131]. Here, CRP is linked to Neonatal sepsis.