When comparing the lipid parameters of patients with CHD in terms of the Apo CIII gene polymorphism, we found that in the Kazakhs with the S1S1 genotype the triglyceride level was significantly increased in comparison with the S1S2 heterozygotes (2,5 ± 0,07 mmol/l) and homozygotes on the S2 alleles (S2S2 2,1 ± 0,08 mmol/l), and was (2,8 ± 0,10 mmol/l, p < 0.05). Here, APOC3 is linked to coronary artery disorder.