Inflammation is a natural bodily response to damage or infection that is generally mediated by proinflammatory cytokines such as interleukin 1 beta (IL-1β), interleukin 6 (IL-6), and tumour necrosis factor alpha (TNFα), in addition to lipidic mediators such as prostaglandins and leukotrienes. This evidence concerns the gene IL1B and infection.