Bagadi et al. reported that Dab2 was lost in all the breast cancer cell lines containing MDA-MB-23117; conversely, Cheong et al. hold opinions that it was weak positive not absent expression of Dab2 in MDA-MB-231.27 More interestingly, we and other researchers found that both lung cancer and 60% of TCC cell lines showed weak to moderate positive expression of Dab2 protein.14,25 Thus, there is not enough evidence to determine that whether the loss or weak positive of Dab2 expressions are analogous in all the human malignant cancer cell lines (P = 0.85). Here, DAB2 is linked to breast carcinoma.