It requires frequent self-monitoring of blood glucose, exercise, dietary modifications and administration of medications and/ or insulin.1-3 Non-adherence to prescribed treatment schedule continues to be a major problem the world over especially for medications in chronic diseases.4,5 The diabetes control and complication trial (DCCT) and other intervention studies6-10 demonstrated that achieving optimal glucose control through adherence to medications, exercise and diet prevents or minimize serious long term complications.1-4,11-13. This evidence concerns the gene INS and diabetes mellitus.