NUMB and hepatocellular carcinoma: In the 107 cases examined, High Numb expression was detected in 43 (40.19%) HCC specimens, whereas only 22 (20.60%) of the nontumor specimens(Table 1).Next, clinical association analysis by the Pearson chi-square test revealed that Numb expression in HCC tumors was significantly associated with poor prognostic for HCC patients.