HSPA5 and neoplasm: The rate of GRP78 expression was found to be closely related to tumor size (>3.1 cm, P = 0.001), tumor stage (T3-T4, P = 0.001), lymphatic metastasis (N1-3, P = 0.000), distant metastasis (M1, P = 0.033), pathologic stage (III-IV, P = 0.000), and histological grade (G3-G4, P = 0.018).