TFAP2B and metastatic malignant neoplasm in the lymph nodes: We also used a univariate analysis to evaluate associations between the patient prognosis and several clinicopathologic factors, including TFAP2B expression (score of 2+ vs. 0, 1+), gender (male vs. female), age (≥ 60 vs. < 60 years), pT stage (tumor size, T3-T4 vs. T1-T2), and pN stage (lymph node metastasis, N1–N2-N3–N4 vs. N0).