CD44 and colorectal cancer: In order to further understand the clinical significance of EpCAMhigh/CD44+ colorectal cancer cells, the present study used double immunohistochemical staining to detect the presence of EpCAMhigh/CD44+ cells in 80 cases of colorectal cancer and 10 cases of corresponding liver metastases to explore the correlation between these cells and the biological behavior of colorectal cancer.