MTDH and neoplasm: The results indicated that increased expression of AEG-1 was significantly correlated with the differentiation degree (P<0.001), depth of tumor infiltration (T stage; P<0.001), the N stage (P=0.003) and the M stage (P=0.013), whereas AEG-1 was not found to correlate with age, gender, tumor size or histological type.