In Table I, the data demonstrates that compared with the control group, the NSCLC group had a low positive rate of semaphorin-3A expression (36.17 vs. 75.00%, respectively) and a high positive rate of MMP-14 (75.53 vs. 25.00%, respectively), and the difference was considered to be statistically significant (P<0.05). The gene discussed is MMP14; the disease is non-small cell lung carcinoma.