TP53 and non-small cell lung carcinoma: While BRMS1 KD induction of both migration and invasion occurs in HBEC3 cells with a genomic background of p53 KD and oncogenic K-RasV12, we observed that BRMS1 KD enhances migration and invasion in almost all tested NSCLC cell lines, regardless of the status of p53 and K-Ras.