MICB and dengue disease: In our data, after adjusting the association for HLA class II associated alleles the most strongly associated marker in the class I region is rs3094014 (p<0.02) which is in LD with both the MICB (r2 0.76 for rs3132468 associated with dengue fever) and MICA (r2 0.90 for rs2596542 reported to be associated with hepatitis C virus induced hepato cellular carcinoma) using European 1000 genomes and HapMap data and may therefore represent the same signal.