LGALS1 and cancer: Knowing that galectin-1 expression is correlated with cell metastatic potential [18], [53] and contributes to tumor progression and resistance after conventional cancer therapeutic modalities [18], the ability of PcGal16 to reduce the levels of galectin-1 after its uptake and/or photoactivation prompted us to envisage PcGal16 as a potential candidate for cancer treatment.