We reviewed the literature and found mutations in PROM1 can lead to several diseases (Table 3), including Stargardt disease (STGD4) [22], [23], retinitis pigmentosa (RP41) [24]–[28], autosomal dominant cone-rod dystrophy (CORD12, CRD) [16], macular dystrophy (MCDR2) [29] and autosomal recessive cone-rod dystrophy (CRD) [21]. The gene discussed is PROM1; the disease is Macular dystrophy.