However, it remains unclear whether this inconsistency is methodological in nature (e.g., the subjective dietary surveys used to capture AA intake) since biomarkers of both AA (and oxidative stress) present more consistent results favouring an important role for AA in cognitive health; (3) there are genetic (SVCT1 and SVCT2 SNPs) and non-genetic (e.g., age) factors that modulate AA absorption and assimilation, which could indicate an increased demand for AA in subsets of the population such as the elderly and those with an AD diagnosis. Here, SLC23A2 is linked to Alzheimer disease.