We here aimed to evaluate the immunohistochemistry expression of ILT4 and IL-10 in a series of invasive ductal and lobular breast carcinomas; analyze the association between ILT4 and IL-10 expression; and discuss their role in breast cancer development through assaying the relationship between ILT4/IL-10 expression and prognostic factors. Here, LILRB2 is linked to breast cancer.