For the clinical diagnosis of sepsis, the area under the ROC curve (AUC with 95% CI) for PCT (0.673 [0.621 – 0.723]) differed significantly from those of BNP (0.526 [0.472 – 0.580], P < 0.001) and NGAL (0.509 [0.455 – 0.564], P = 0.005). Here, NPPB is linked to Sepsis.