F2 and metastatic malignant neoplasm in the lymph nodes: Table 3 shows the results of the univariate and multivariate analyses. Four risk factors(prothrombin time, Child-Pugh grade, portal/hepatic vein invasion and lymph node metastasis) were associated with overall survival on univariate analysis (P = 0.039, 0.012, 0.042 and 0.036, respectively). Total bilirubin at a p value of 0.051 had almost reached to become a significant risk factor of overall survival. On multivariate analysis lymph node metastasis remained as the only independent risk factor of overall survival (P = 0.040).