EPHA2 and familial pancreatic carcinoma: Transduction experiments with EphA2-positive cell lines PANC-1, MIA PaCa-2, Capan-1 (pancreatic cancer) and C8161 (melanoma) yielded results that were similar for the respective cell lines: All three viruses pseudotyped with the short-shafted YSA fibers showed transduction, which was substantially stronger than for the control viruses without YSA peptide (Fig. 2C; 10-fold to 35-fold increase in β-Gal activity).