TP53 and lung carcinoma: TP53 incurred several deleterious mutations in our sample set of 76 lung cancers, mostly along the DNA-binding domain encoded from exon 5 (27.8%), 6 (16.7%), 7 (33.3%), 8 (16.7%), and along the oligomerization domain encoded from exon 10 (15.6%) (Fig. 4A–C).