Thus, it is possible that down-regulated miR-125a (Figure 5) in PBMC from PTSD patients may be responsible for IFN-γ up-regulation (Figure 4), and the increased level of IFN-γ may be responsible for induction of a Th1 cell increase in PBMC from PTSD patients (Figure 3). The gene discussed is IFNG; the disease is post-traumatic stress disorder.