SP1 and neoplasm: Cord formation was assessed using High Content Imaging [19]–[21] following knockdown of VEGF and bFGF receptors (VEGFR2 and FGFR1, respectively) as well as the transcription factors FOXO1 in the ADSC/ECFC co-culture system and SP1 in a tumor driven co-culture system using lentiviral delivered short hairpin RNA (shRNA).