KERA and congenital stromal corneal dystrophy: Mutations in the SLRPs have been associated with abnormalities of corneal clarity and curvature, with missense and nonsense mutations in KERA implicated in autosomal recessive cornea plana (CNA2 [MIM 217300]) [13]–[20], and nonsense mutations in DCN involved in congenital hereditary stromal dystrophy (CSCD [MIM 610048]) [21]–[23].