We first determined BTK expression in several lymphoma cell lines (Daudi Burkitt's Lymphoma line, and DB, Toledo, and RC-K8 Diffuse Large B-Cell Lymphoma (DLBCL) lines) and one T-cell leukemia line (Jurkat) by Western blot (Supplementary Fig. S1). This evidence concerns the gene BTK and diffuse large B-cell lymphoma.