A progressive, statistically significant increase (p < .001) of mean values of urinary 8-iso-PGF2α and of serum sNOX2-dp, CK-18, ALT, gamma-glutamil-transpeptidase (GGT) and HOMA-IR was observed from the group without fatty liver to the groups with mild, moderate and severe steatosis, while a decreasing trend was observed for serum adiponectin. Here, GPT is linked to fatty liver disease.