Now, CD133 may represent a putative cancer stem cell marker in many solid tumors, such as human colon cancer [7,8], breast cancer [9,10], gastric cancer [11,12], glioblastoma [13], lung cancer [14,15], liver cancer [16,17], pancreatic cancer [18], prostate cancer [19], and cholangiocarcinoma [20]. The gene discussed is PROM1; the disease is cancer.