The results demonstrated that the CORT levels in both groups of CIS mice were far higher than that in control mice (n = 6 for each group, F(2, 15) = 7.201, p = 0.006, Figure 5D), indicating that the elevated CORT in plasma could last for at least 10 days after the cessation of CIS exposure. This evidence concerns the gene CORT and in situ carcinoma.