Up to now, various new biomarkers, such as Neutrophil Gelatinase Associated Lipocalin (NGAL), Kidney Injury Molecule-1(KIM-1), cystatin C, Interlukine-18 (IL-18), N-acetyl-β2-(D)-glucosaminidase(NAG), and β2-microglobulin, have been studied for early and more accurate diagnosis of AKI (12,17). The gene discussed is IL18; the disease is acute kidney injury.